InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DEGS1

Summary

InnateDB Protein

IDBP-682382.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DEGS1

Protein Name

Sphingolipid delta(4)-desaturase DES1

Synonyms

DES1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016887

InnateDB Gene

IDBG-630901 (DEGS1)

Protein Structure

UniProt Annotation

Function

Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Biological Process

GO:0006629	lipid metabolic process
GO:0006631	fatty acid metabolic process
GO:0006633	fatty acid biosynthetic process
GO:0030148	sphingolipid biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane