Bos taurus Protein: SPACA3
Summary
InnateDB Protein IDBP-682461.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPACA3
Protein Name Sperm acrosome membrane-associated protein 3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000449
InnateDB Gene IDBG-630975 (SPACA3)
Protein Structure
UniProt Annotation
Function Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003796 lysozyme activity
GO:0005515 protein binding
Biological Process
GO:0016998 cell wall macromolecule catabolic process
GO:0035036 sperm-egg recognition
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005576 extracellular region
GO:0005764 lysosome
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID
InterPro IPR000974 Glycoside hydrolase, family 22, lysozyme
IPR001916 Glycoside hydrolase, family 22
IPR023346 Lysozyme-like domain
PFAM PF00062
PF13406
PRINTS PR00137
PR00135
PIRSF
SMART SM00263
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6QQ77
PhosphoSite PhosphoSite-
TrEMBL F1MES9
UniProt Splice Variant
Entrez Gene 617955
UniGene Bt.54326
RefSeq NP_001098477
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149686 DAAA02048501
GenPept AAI49687