InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ADAP2

Summary

InnateDB Protein

IDBP-682592.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADAP2

Protein Name

ArfGAP with dual PH domains 2

Synonyms

CENTA2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004328

InnateDB Gene

IDBG-631091 (ADAP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008060	ARF GTPase activator activity
GO:0008270	zinc ion binding
GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
GO:0046872	metal ion binding

Biological Process

GO:0007507	heart development
GO:0032312	regulation of ARF GTPase activity
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001164 Arf GTPase activating protein
IPR001849 Pleckstrin homology domain

PFAM

PF01412
PF00169

PRINTS

PR00405

PIRSF

SMART

SM00105
SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MZC2

UniProt Splice Variant

Entrez Gene

534106

UniGene

Bt.41143

RefSeq

NP_001179727

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02048521 DAAA02048522 DAAA02048523

GenPept