Version 5.4
| Bos taurus Protein: GPR84 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-682636.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | GPR84 | ||||||||
| Protein Name | G-protein coupled receptor 84 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000020710 | ||||||||
| InnateDB Gene | IDBG-631137 (GPR84) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR017452 GPCR, rhodopsin-like, 7TM IPR019430 7TM GPCR, serpentine receptor class x (Srx) IPR023041 Glucose receptor Git3, N-terminal |
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| PFAM |
PF00001
PF10328 PF11710 |
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| PRINTS |
PR00237
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q2KI97 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 540044 | ||||||||
| UniGene | Bt.66715 | ||||||||
| RefSeq | NP_001033657 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC112718 BT030483 | ||||||||
| GenPept | AAI12719 ABQ12923 | ||||||||