Version 5.4
Bos taurus Protein: DSE
Summary
InnateDB Protein IDBP-682657.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSE
Protein Name Dermatan-sulfate epimerase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006855
InnateDB Gene IDBG-631151 (DSE)
Protein Structure
UniProt Annotation
Function Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. {ECO:0000269PubMed:16505484}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016853 isomerase activity
GO:0047757 chondroitin-glucuronate 5-epimerase activity
Biological Process
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0030206 chondroitin sulfate biosynthetic process
GO:0030208 dermatan sulfate biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008929 Chondroitin AC/alginate lyase
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P0C2H4
PhosphoSite PhosphoSite-
TrEMBL F1MM96
UniProt Splice Variant
Entrez Gene 514028
UniGene Bt.48522
RefSeq NP_001106703
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025791 DAAA02025792 DAAA02025793
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca