InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ORC6

Summary

InnateDB Protein

IDBP-682726.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ORC6

Protein Name

Origin recognition complex subunit 6

Synonyms

ORC6L;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000002438

InnateDB Gene

IDBG-631214 (ORC6)

Protein Structure

UniProt Annotation

Function

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding

Biological Process

GO:0006260	DNA replication
GO:0006261	DNA-dependent DNA replication

Cellular Component

GO:0000808	origin recognition complex
GO:0005634	nucleus
GO:0005664	nuclear origin of replication recognition complex
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR008721 Origin recognition complex, subunit 6

PFAM

PF05460

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2HJF3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

515476

UniGene

Bt.3068

RefSeq

NP_001039666

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC105472

GenPept

AAI05473