Version 5.4
Bos taurus Protein: ATP5G2
Summary
InnateDB Protein IDBP-682744.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP5G2
Protein Name ATP synthase lipid-binding protein, mitochondrial
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007538
InnateDB Gene IDBG-631229 (ATP5G2)
Protein Structure
UniProt Annotation
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
Subcellular Localization Mitochondrion membrane; Multi-pass membrane protein.
Disease Associations Note=This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease).
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
GO:0015078 hydrogen ion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0015986 ATP synthesis coupled proton transport
GO:0015991 ATP hydrolysis coupled proton transport
GO:0015992 proton transport
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)
Protein Structure and Domains
PDB ID
InterPro IPR000454 ATPase, F0 complex, subunit C
IPR002379 V-ATPase proteolipid subunit C-like domain
PFAM PF00137
PRINTS PR00124
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P07926
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 337887
UniGene Bt.64851
RefSeq NP_788786
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB098947 BC111613 X05219
GenPept AAI11614 BAC56437 CAA28846

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca