Version 5.4
Bos taurus Protein: IL33
Summary
InnateDB Protein IDBP-682770.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL33
Protein Name interleukin-33
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000024412
InnateDB Gene IDBG-631251 (IL33)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005515 protein binding
GO:0046556 alpha-L-arabinofuranosidase activity
Biological Process
GO:0002686 negative regulation of leukocyte migration
GO:0002826 negative regulation of T-helper 1 type immune response
GO:0002830 positive regulation of type 2 immune response
GO:0010628 positive regulation of gene expression
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032689 negative regulation of interferon-gamma production
GO:0032736 positive regulation of interleukin-13 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032754 positive regulation of interleukin-5 production
GO:0032755 positive regulation of interleukin-6 production
GO:0043032 positive regulation of macrophage activation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046373 L-arabinose metabolic process
GO:0050729 positive regulation of inflammatory response
GO:0051024 positive regulation of immunoglobulin secretion
GO:0051025 negative regulation of immunoglobulin secretion
GO:0090197 positive regulation of chemokine secretion
GO:0097191 extrinsic apoptotic signaling pathway
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR007934 Alpha-L-arabinofuranosidase B
PFAM PF05270
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q08DU3
UniProt Splice Variant
Entrez Gene 507054
UniGene Bt.22094
RefSeq NP_001068765
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123562 DAAA02022665 DAAA02022666 DAAA02022667
GenPept AAI23563

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca