InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PUS1

Summary

InnateDB Protein

IDBP-682867.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PUS1

Protein Name

Pseudouridine synthase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017270

InnateDB Gene

IDBG-631334 (PUS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0009982	pseudouridine synthase activity
GO:0016853	isomerase activity
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001522	pseudouridine synthesis
GO:0008033	tRNA processing
GO:0009451	RNA modification
GO:0031119	tRNA pseudouridine synthesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

InterPro

IPR001406 Pseudouridine synthase I, TruA
IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain
IPR020103 Pseudouridine synthase, catalytic domain

PFAM

PF01416

PRINTS

PIRSF

PIRSF001430

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite