Version 5.4
Bos taurus Protein: RARG
Summary
InnateDB Protein IDBP-682895.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RARG
Protein Name retinoic acid receptor, gamma
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009984
InnateDB Gene IDBG-631366 (RARG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0003708 retinoic acid receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0046965 retinoid X receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001843 neural tube closure
GO:0002063 chondrocyte development
GO:0002068 glandular epithelial cell development
GO:0003406 retinal pigment epithelium development
GO:0003417 growth plate cartilage development
GO:0003430 growth plate cartilage chondrocyte growth
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0008285 negative regulation of cell proliferation
GO:0009952 anterior/posterior pattern specification
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0031076 embryonic camera-type eye development
GO:0032331 negative regulation of chondrocyte differentiation
GO:0032526 response to retinoic acid
GO:0035116 embryonic hindlimb morphogenesis
GO:0035264 multicellular organism growth
GO:0043010 camera-type eye development
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043068 positive regulation of programmed cell death
GO:0043401 steroid hormone mediated signaling pathway
GO:0045596 negative regulation of cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048048 embryonic eye morphogenesis
GO:0048384 retinoic acid receptor signaling pathway
GO:0048608 reproductive structure development
GO:0048732 gland development
GO:0060041 retina development in camera-type eye
GO:0060173 limb development
GO:0060324 face development
GO:0060348 bone development
GO:0060349 bone morphogenesis
GO:0060429 epithelium development
GO:0060534 trachea cartilage development
GO:0060740 prostate gland epithelium morphogenesis
GO:0061037 negative regulation of cartilage development
GO:0070384 Harderian gland development
GO:0071300 cellular response to retinoic acid
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID
InterPro IPR000003 Retinoid X receptor/HNF4
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR003070 Orphan nuclear receptor
IPR003078 Retinoic acid receptor
IPR008946 Nuclear hormone receptor, ligand-binding
PFAM PF00104
PF00105
PRINTS PR00545
PR00047
PR00398
PR01284
PR01292
PIRSF
SMART SM00430
SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q08DD4
UniProt Splice Variant
Entrez Gene 540425
UniGene Bt.53782
RefSeq NP_001124228
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123809 DAAA02012865
GenPept AAI23810

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca