Version 5.4
Bos taurus Protein: APOA1BP
Summary
InnateDB Protein IDBP-683042.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOA1BP
Protein Name Apolipoprotein A-I-binding protein
Synonyms AIBP;
Species Bos taurus
Ensembl Protein ENSBTAP00000000518
InnateDB Gene IDBG-631503 (APOA1BP)
Protein Structure
UniProt Annotation
Function Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. {ECO:0000255HAMAP-Rule:MF_03159}.
Subcellular Localization Mitochondrion {ECO:0000255HAMAP- Rule:MF_03159}. Secreted {ECO:0000255HAMAP-Rule:MF_03159}. Note=In sperm, secretion gradually increases during capacitation. {ECO:0000255HAMAP-Rule:MF_03159}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0052856 NADHX epimerase activity
Biological Process
GO:0008152 metabolic process
GO:0051289 protein homotetramerization
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005929 cilium
GO:0044297 cell body
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR004443 YjeF N-terminal domain
PFAM PF03853
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6QRN6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 404132
UniGene Bt.91150
RefSeq NP_991365
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY528250 BC114830
GenPept AAI14831 AAS20598

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca