Version 5.4
Bos taurus Protein: TMEM97
Summary
InnateDB Protein IDBP-683089.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM97
Protein Name Transmembrane protein 97
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000010666
InnateDB Gene IDBG-631550 (TMEM97)
Protein Structure
UniProt Annotation
Function Plays a role as a regulator of cellular cholesterol homeostasis. {ECO:0000250}.
Subcellular Localization Nucleus membrane {ECO:0000250}. Rough endoplasmic reticulum {ECO:0000250}. Cell membrane {ECO:0000250}. Lysosome {ECO:0000250}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localized in sterol-depleted cells at cell membrane and in lysosomes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0042632 cholesterol homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR016964 Transmembrane protein 6/97
PFAM PF10914
PRINTS
PIRSF PIRSF031032
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MHW7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 511378
UniGene Bt.4715
RefSeq NP_001029575
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC104594 BT029797
GenPept AAI04595 ABM06065

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca