Version 5.4
Bos taurus Protein: NME7
Summary
InnateDB Protein IDBP-683238.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NME7
Protein Name Nucleoside diphosphate kinase 7
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000044149
InnateDB Gene IDBG-631675 (NME7)
Protein Structure
UniProt Annotation
Function Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0003351 epithelial cilium movement
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0007368 determination of left/right symmetry
GO:0007420 brain development
GO:0009117 nucleotide metabolic process
GO:0016310 phosphorylation
GO:0042073 intraciliary transport
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway
GO:0060972 left/right pattern formation
Cellular Component
GO:0005813 centrosome
GO:0036064 ciliary basal body
Protein Structure and Domains
PDB ID
InterPro IPR001564 Nucleoside diphosphate kinase
IPR006602 Uncharacterised domain DM10
IPR011410 Nucleoside diphosphate kinase, NDK7
PFAM PF00334
PRINTS PR01243
PIRSF PIRSF036503
SMART SM00562
SM00676
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5E9Y9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 534611
UniGene
RefSeq NP_001015656
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109996 BT020780
GenPept AAI09997 AAX08797

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca