InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NAGK

Summary

InnateDB Protein

IDBP-683336.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NAGK

Protein Name

N-acetyl-D-glucosamine kinase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000019528

InnateDB Gene

IDBG-631775 (NAGK)

Protein Structure

UniProt Annotation

Function

Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0009384	N-acylmannosamine kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0045127	N-acetylglucosamine kinase activity

Biological Process

GO:0006044	N-acetylglucosamine metabolic process
GO:0016310	phosphorylation
GO:0019262	N-acetylneuraminate catabolic process
GO:0046835	carbohydrate phosphorylation

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002731 ATPase, BadF/BadG/BcrA/BcrD type

PFAM

PF01869

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3SZM9

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

508132

UniGene

Bt.4387

RefSeq

NP_001029486

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102780

GenPept

AAI02781