InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DIS3

Summary

InnateDB Protein

IDBP-683357.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DIS3

Protein Name

DIS3 mitotic control homolog (S. cerevisiae)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026500

InnateDB Gene

IDBG-631725 (DIS3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000175	3'-5'-exoribonuclease activity
GO:0004519	endonuclease activity
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0016075	rRNA catabolic process
GO:0043547	positive regulation of GTPase activity
GO:0071034	CUT catabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic

Cellular Component

GO:0000176	nuclear exosome (RNase complex)
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002716 PIN domain
IPR016024 Armadillo-type fold
IPR029060 PIN domain-like

PFAM

PF01850
PF10130
PF13470
PF13638

PRINTS

PIRSF

SMART

SM00670

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1N1R4

UniProt Splice Variant

Entrez Gene

767887

UniGene

RefSeq

XP_001249406

HUGO

HGNC:20604

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02033485 DAAA02033486

GenPept