Bos taurus Protein: ALOX5
Summary
InnateDB Protein IDBP-683590.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALOX5
Protein Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027080
InnateDB Gene IDBG-632004 (ALOX5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004051 arachidonate 5-lipoxygenase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0002540 leukotriene production involved in inflammatory response
GO:0006691 leukotriene metabolic process
GO:0006954 inflammatory response
GO:0019370 leukotriene biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005641 nuclear envelope lumen
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016363 nuclear matrix
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR001024 PLAT/LH2 domain
IPR001885 Lipoxygenase, mammalian
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR013819 Lipoxygenase, C-terminal
PFAM PF01477
PF00305
PRINTS PR00467
PR00087
PIRSF
SMART SM00308
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9BEG3
UniProt Splice Variant
Entrez Gene 404074
UniGene Bt.7090
RefSeq NP_001179721
HUGO HGNC:435
OMIM
CCDS
HPRD
IMGT
EMBL AJ306424 DAAA02062239 DAAA02062240 DAAA02062241
GenPept CAC33511