Version 5.4
Bos taurus Protein: NCOR2
Summary
InnateDB Protein IDBP-683594.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCOR2
Protein Name nuclear receptor corepressor 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000034171
InnateDB Gene IDBG-631930 (NCOR2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 107 interaction(s) predicted by orthology.
Predicted by orthology
Total 107 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003714 transcription corepressor activity
GO:0005112 Notch binding
GO:0005515 protein binding
GO:0042826 histone deacetylase binding
GO:0043565 sequence-specific DNA binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001701 in utero embryonic development
GO:0003007 heart morphogenesis
GO:0021537 telencephalon development
GO:0021846 cell proliferation in forebrain
GO:0030900 forebrain development
GO:0042593 glucose homeostasis
GO:0045599 negative regulation of fat cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050872 white fat cell differentiation
GO:0060509 Type I pneumocyte differentiation
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0016020 membrane
GO:0016363 nuclear matrix
GO:0016604 nuclear body
GO:0017053 transcriptional repressor complex
Protein Structure and Domains
PDB ID
InterPro IPR001005 SANT/Myb domain
IPR009057 Homeodomain-like
PFAM PF00249
PRINTS
PIRSF
SMART SM00717
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3X7K5
UniProt Splice Variant
Entrez Gene
UniGene Bt.63326
RefSeq
HUGO HGNC:7673
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045216 DAAA02045217 DAAA02045218 DAAA02045219 DAAA02045220 DAAA02045221 DAAA02045222 DAAA02045223
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca