InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SMC5

Summary

InnateDB Protein

IDBP-683707.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMC5

Protein Name

structural maintenance of chromosomes 5

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053371

InnateDB Gene

IDBG-632042 (SMC5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0004871	signal transducer activity
GO:0005515	protein binding

Biological Process

GO:0000722	telomere maintenance via recombination
GO:0000724	double-strand break repair via homologous recombination
GO:0006281	DNA repair
GO:0006355	regulation of transcription, DNA-templated
GO:0007165	signal transduction
GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842	positive regulation of mitotic metaphase/anaphase transition
GO:0090398	cellular senescence

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005634	nucleus
GO:0016605	PML body
GO:0030054	cell junction
GO:0030915	Smc5-Smc6 complex

Protein Structure and Domains

PDB ID

InterPro

IPR003395 RecF/RecN/SMC, N-terminal
IPR015988 STAT transcription factor, coiled coil
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02463

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02022832 DAAA02022833 DAAA02022834

GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca