InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NEK8

Summary

InnateDB Protein

IDBP-683710.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NEK8

Protein Name

NIMA (never in mitosis gene a)- related kinase 8

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020643

InnateDB Gene

IDBG-632103 (NEK8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0009887	organ morphogenesis
GO:0035330	regulation of hippo signaling

Cellular Component

GO:0072372

primary cilium

Protein Structure and Domains

PDB ID

InterPro

IPR000408 Regulator of chromosome condensation, RCC1
IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00415
PF00069
PF07714

PRINTS

PR00633
PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt