InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LOC783305

Summary

InnateDB Protein

IDBP-683715.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LOC783305

Protein Name

TNF receptor-associated factor 4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000050075

InnateDB Gene

IDBG-632122 (LOC783305)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.

Predicted by orthology
Total	56 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005164	tumor necrosis factor receptor binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019901	protein kinase binding
GO:0031625	ubiquitin protein ligase binding
GO:0031996	thioesterase binding
GO:0046872	metal ion binding
GO:0050699	WW domain binding

Biological Process

GO:0007165	signal transduction
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0007585	respiratory gaseous exchange
GO:0016567	protein ubiquitination
GO:0030323	respiratory tube development
GO:0042981	regulation of apoptotic process
GO:0045860	positive regulation of protein kinase activity
GO:0046330	positive regulation of JNK cascade
GO:0090073	positive regulation of protein homodimerization activity

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001293 Zinc finger, TRAF-type
IPR001841 Zinc finger, RING-type
IPR002083 MATH
IPR008974 TRAF-like
IPR012227 TNF receptor-associated factor TRAF
IPR018957 Zinc finger, C3HC4 RING-type

PFAM

PF13639
PF14634
PF00917
PF00097

PRINTS

PIRSF

PIRSF015614

SMART

SM00184
SM00061

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt