Version 5.4
Bos taurus Protein: PRKAR2B
Summary
InnateDB Protein IDBP-683725.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRKAR2B
Protein Name cAMP-dependent protein kinase type II-beta regulatory subunit
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000019916
InnateDB Gene IDBG-632130 (PRKAR2B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004862 cAMP-dependent protein kinase inhibitor activity
GO:0005515 protein binding
GO:0008603 cAMP-dependent protein kinase regulator activity
GO:0019901 protein kinase binding
GO:0031625 ubiquitin protein ligase binding
GO:0034236 protein kinase A catalytic subunit binding
Biological Process
GO:0001932 regulation of protein phosphorylation
GO:0006631 fatty acid metabolic process
GO:0007612 learning
GO:2000480 negative regulation of cAMP-dependent protein kinase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005886 plasma membrane
GO:0005952 cAMP-dependent protein kinase complex
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
GO:0097546 ciliary base
Protein Structure and Domains
PDB ID
InterPro IPR000595 Cyclic nucleotide-binding domain
IPR002373 cAMP/cGMP-dependent protein kinase
IPR003117 Dimerization-anchoring domain of cAMP-dependent protein kinase, regulatory subunit
IPR012198 cAMP-dependent protein kinase regulatory subunit
IPR018490 Cyclic nucleotide-binding-like
PFAM PF00027
PF02197
PRINTS PR00103
PIRSF PIRSF000548
SMART SM00100
SM00394
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6Q9S4
UniProt Splice Variant
Entrez Gene 282463
UniGene Bt.462
RefSeq NP_777074
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010575 DAAA02010576 DAAA02010577
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca