Version 5.4
Bos taurus Protein: BT.65045
Summary
InnateDB Protein IDBP-683820.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.65045
Protein Name histone-lysine N-methyltransferase SETD8
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000055591
InnateDB Gene IDBG-632200 (BT.65045)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0016279 protein-lysine N-methyltransferase activity
GO:0018024 histone-lysine N-methyltransferase activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0018026 peptidyl-lysine monomethylation
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR001214 SET domain
IPR016858 Histone H4-K20 methyltransferase
PFAM PF00856
PRINTS
PIRSF PIRSF027717
SMART SM00317
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3N163
UniProt Splice Variant
Entrez Gene 532622
UniGene Bt.65045
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02045235 DAAA02045236 DAAA02045237
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca