Version 5.4
Bos taurus Protein: STRN3
Summary
InnateDB Protein IDBP-683843.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STRN3
Protein Name Striatin-3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029119
InnateDB Gene IDBG-632240 (STRN3)
Protein Structure
UniProt Annotation
Function Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Predicted by orthology
Total 52 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0032403 protein complex binding
GO:0051721 protein phosphatase 2A binding
GO:0070016 armadillo repeat domain binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000159 protein phosphatase type 2A complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR013258 Striatin, N-terminal
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF08232
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A5D7H2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 516375
UniGene Bt.98133
RefSeq NP_001091511
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC140553
GenPept AAI40554

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca