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InnateDB Protein
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IDBP-683853.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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AP4S1
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Protein Name
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AP-4 complex subunit sigma-1
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000043387
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InnateDB Gene
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IDBG-632245 (AP4S1)
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Protein Structure
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| Function |
Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. {ECO:0000250}.
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| Subcellular Localization |
Golgi apparatus, trans-Golgi network {ECO:0000250}. Membrane, coated pit {ECO:0000250}. Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells (By similarity). {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
6 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0008565
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protein transporter activity
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR011012
Longin-like domain
IPR016635
Adaptor protein complex, sigma subunit
IPR022775
AP complex, mu/sigma subunit
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| PFAM |
PF01217
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| PRINTS |
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| PIRSF |
PIRSF015588
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q3ZBB6
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
618267
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| UniGene |
Bt.49383
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| RefSeq |
NP_001035693
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| HUGO |
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
BC103455
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| GenPept |
AAI03456
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Version 5.4