InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NDUFAF4

Summary

InnateDB Protein

IDBP-683873.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDUFAF4

Protein Name

NADH dehydrogenase

Synonyms

C9H6ORF66; HRPAP20;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004122

InnateDB Gene

IDBG-632272 (NDUFAF4)

Protein Structure

UniProt Annotation

Function

Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (By similarity). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005516	calmodulin binding

Biological Process

GO:0010257	NADH dehydrogenase complex assembly
GO:0032981	mitochondrial respiratory chain complex I assembly

Cellular Component

GO:0005739	mitochondrion
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

InterPro

IPR009622 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

PFAM

PF06784

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A4FUH5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

615440

UniGene

Bt.36178

RefSeq

NP_001076985

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC114895

GenPept

AAI14896