Version 5.4
Homo sapiens Protein: MAGEF1
Summary
InnateDB Protein IDBP-68390.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGEF1
Protein Name melanoma antigen family F, 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000315064
InnateDB Gene IDBG-68388 (MAGEF1)
Protein Structure
UniProt Annotation
Function May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269PubMed:20864041}.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 9 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002190 MAGE protein
PFAM PF01454
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HAY2
PhosphoSite PhosphoSite-Q9HAY2
TrEMBL
UniProt Splice Variant
Entrez Gene 64110
UniGene Hs.306123
RefSeq NP_071432
HUGO HGNC:29639
OMIM 609267
CCDS CCDS3269
HPRD 14348
IMGT
EMBL AC107294 AF295378 AF320910 BC010056
GenPept AAG30208 AAG38606 AAH10056

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca