InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RORB

Summary

InnateDB Protein

IDBP-683922.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RORB

Protein Name

RAR-related orphan receptor B

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028921

InnateDB Gene

IDBG-632316 (RORB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030522	intracellular receptor signaling pathway
GO:0035881	amacrine cell differentiation
GO:0042462	eye photoreceptor cell development
GO:0042752	regulation of circadian rhythm
GO:0043401	steroid hormone mediated signaling pathway
GO:0045668	negative regulation of osteoblast differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0046548	retinal rod cell development
GO:0046549	retinal cone cell development
GO:0060041	retina development in camera-type eye

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR001728 Thyroid hormone receptor
IPR003079 Nuclear receptor ROR
IPR008946 Nuclear hormone receptor, ligand-binding

PFAM

PF00104
PF00105

PRINTS

PR00047
PR00398
PR00546
PR01293

PIRSF

SMART

SM00430
SM00399

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt