Version 5.4
Bos taurus Protein: TNFRSF8
Summary
InnateDB Protein IDBP-683983.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNFRSF8
Protein Name tumor necrosis factor receptor superfamily, member 8
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000047653
InnateDB Gene IDBG-632372 (TNFRSF8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process
GO:0043065 positive regulation of apoptotic process
GO:0045556 positive regulation of TRAIL biosynthetic process
GO:0071260 cellular response to mechanical stimulus
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001368 TNFR/NGFR cysteine-rich region
IPR020416 Tumour necrosis factor receptor 8
PFAM PF00020
PRINTS PR01923
PIRSF
SMART SM00208
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N0U5
UniProt Splice Variant
Entrez Gene 614780
UniGene
RefSeq XP_002694100
HUGO HGNC:11923
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02042945 DAAA02042946 DAAA02042947
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca