InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PCSK5

Summary

InnateDB Protein

IDBP-684071.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PCSK5

Protein Name

proprotein convertase subtilisin/kexin type 5

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000036514

InnateDB Gene

IDBG-632432 (PCSK5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004175	endopeptidase activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity
GO:0016787	hydrolase activity
GO:0042277	peptide binding

Biological Process

GO:0001822	kidney development
GO:0002001	renin secretion into blood stream
GO:0006465	signal peptide processing
GO:0006508	proteolysis
GO:0007507	heart development
GO:0007566	embryo implantation
GO:0009952	anterior/posterior pattern specification
GO:0016485	protein processing
GO:0016486	peptide hormone processing
GO:0019058	viral life cycle
GO:0030323	respiratory tube development
GO:0035108	limb morphogenesis
GO:0042089	cytokine biosynthetic process
GO:0043043	peptide biosynthetic process
GO:0048566	embryonic digestive tract development
GO:0048706	embryonic skeletal system development

Cellular Component

GO:0005615	extracellular space
GO:0005794	Golgi apparatus
GO:0030141	secretory granule

Protein Structure and Domains

PDB ID

InterPro

IPR000209 Peptidase S8/S53 domain
IPR000742 Epidermal growth factor-like domain
IPR002884 Proprotein convertase, P
IPR006212 Furin-like repeat
IPR008979 Galactose-binding domain-like
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR015500 Peptidase S8, subtilisin-related

PFAM

PF00082
PF00008
PF01483

PRINTS

PR00723

PIRSF

SMART

SM00181
SM00261

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt