Version 5.4
Bos taurus Protein: CX3CL1
Summary
InnateDB Protein IDBP-684084.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CX3CL1
Protein Name chemokine (C-X3-C motif) ligand 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000034515
InnateDB Gene IDBG-632469 (CX3CL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008009 chemokine activity
Biological Process
GO:0006935 chemotaxis
GO:0006955 immune response
GO:0019221 cytokine-mediated signaling pathway
GO:0030593 neutrophil chemotaxis
GO:0032914 positive regulation of transforming growth factor beta1 production
GO:0042060 wound healing
GO:0045766 positive regulation of angiogenesis
GO:0048246 macrophage chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0050729 positive regulation of inflammatory response
GO:0051041 positive regulation of calcium-independent cell-cell adhesion
GO:0060055 angiogenesis involved in wound healing
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0005576 extracellular region
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001811 Chemokine interleukin-8-like domain
IPR008097 CX3C chemokine ligand 1
PFAM PF00048
PRINTS PR01721
PIRSF
SMART SM00199
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N6Z2
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:10647
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046519
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca