InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AVPR2

Summary

InnateDB Protein

IDBP-684130.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AVPR2

Protein Name

Vasopressin V2 receptor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000055744

InnateDB Gene

IDBG-632510 (AVPR2)

Protein Structure

UniProt Annotation

Function

Involved in renal water reabsorption (By similarity). Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. {ECO:0000250}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0005000	vasopressin receptor activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007249	I-kappaB kinase/NF-kappaB signaling
GO:0010628	positive regulation of gene expression
GO:0032609	interferon-gamma production
GO:0034097	response to cytokine

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000161 Vasopressin V2 receptor
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001817 Vasopressin receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00898
PR00237
PR00896

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P48044