Version 5.4
Bos taurus Protein: PPP2R3C
Summary
InnateDB Protein IDBP-684144.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP2R3C
Protein Name Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Synonyms C14orf10;
Species Bos taurus
Ensembl Protein ENSBTAP00000012770
InnateDB Gene IDBG-632524 (PPP2R3C)
Protein Structure
UniProt Annotation
Function May regulate MCM3AP phosphorylation through phosphatase recruitment. May play a role in the activation-induced cell death of B-cells (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001782 B cell homeostasis
GO:0002759 regulation of antimicrobial humoral response
GO:0032147 activation of protein kinase activity
GO:0043029 T cell homeostasis
GO:0045579 positive regulation of B cell differentiation
GO:0048536 spleen development
GO:0050864 regulation of B cell activation
GO:0051900 regulation of mitochondrial depolarization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5E9G1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 533147
UniGene Bt.12250
RefSeq NP_001015645
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102393 BT020959
GenPept AAI02394 AAX08976

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca