Version 5.4
Bos taurus Protein: TFAP2B
Summary
InnateDB Protein IDBP-684153.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFAP2B
Protein Name transcription factor AP-2-beta
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027222
InnateDB Gene IDBG-632531 (TFAP2B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0000983 RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001105 RNA polymerase II transcription coactivator activity
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0001158 enhancer sequence-specific DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001822 kidney development
GO:0003091 renal water homeostasis
GO:0006006 glucose metabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007423 sensory organ development
GO:0008284 positive regulation of cell proliferation
GO:0008285 negative regulation of cell proliferation
GO:0010842 retina layer formation
GO:0010960 magnesium ion homeostasis
GO:0030510 regulation of BMP signaling pathway
GO:0035136 forelimb morphogenesis
GO:0035137 hindlimb morphogenesis
GO:0035810 positive regulation of urine volume
GO:0035909 aorta morphogenesis
GO:0042593 glucose homeostasis
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043588 skin development
GO:0045444 fat cell differentiation
GO:0045595 regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048485 sympathetic nervous system development
GO:0050796 regulation of insulin secretion
GO:0055062 phosphate ion homeostasis
GO:0055074 calcium ion homeostasis
GO:0055075 potassium ion homeostasis
GO:0055078 sodium ion homeostasis
GO:0072017 distal tubule development
GO:0072044 collecting duct development
GO:0072210 metanephric nephron development
GO:0097070 ductus arteriosus closure
GO:0097275 cellular ammonia homeostasis
GO:0097276 cellular creatinine homeostasis
GO:0097277 cellular urea homeostasis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR008122 Transcription factor AP-2 beta
IPR013854 Transcription factor AP-2, C-terminal
PFAM PF03299
PRINTS PR01750
PR01748
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0VC35
UniProt Splice Variant
Entrez Gene 540867
UniGene Bt.33532
RefSeq NP_001069715
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120374 DAAA02055234 DAAA02055235 DAAA02055236
GenPept AAI20375

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca