InnateDB Protein
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IDBP-684249.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IL17A
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Protein Name
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Interleukin-17A
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Synonyms
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IL-17; IL17;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000002786
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InnateDB Gene
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IDBG-632619 (IL17A)
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Protein Structure
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Function |
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. {ECO:0000250}.
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Subcellular Localization |
Secreted {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
17 [view]
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Molecular Function |
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Biological Process |
GO:0006954
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inflammatory response
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GO:0032747
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positive regulation of interleukin-23 production
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GO:0045672
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positive regulation of osteoclast differentiation
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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GO:0071347
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cellular response to interleukin-1
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GO:0072537
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fibroblast activation
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GO:1900017
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positive regulation of cytokine production involved in inflammatory response
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Cellular Component |
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PDB ID |
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InterPro |
IPR010345
Interleukin-17 family
IPR020440
Interleukin-17, chordata
IPR029034
Cystine-knot cytokine
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PFAM |
PF06083
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PRINTS |
PR01932
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q687Y7
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q9TUP5
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UniProt Splice Variant |
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Entrez Gene |
282863
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UniGene |
Bt.12772
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RefSeq |
NP_001008412
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AF166487
AF412040
AF416586
EU682381
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GenPept |
AAD46376
AAL08013
AAQ03220
ACD81652
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