Version 5.4
Bos taurus Protein: CRK
Summary
InnateDB Protein IDBP-684314.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRK
Protein Name v-crk sarcoma virus CT10 oncogene homolog (avian)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007443
InnateDB Gene IDBG-632684 (CRK)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 226 interaction(s) predicted by orthology.
Predicted by orthology
Total 226 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005070 SH3/SH2 adaptor activity
GO:0005515 protein binding
GO:0042169 SH2 domain binding
GO:0045309 protein phosphorylated amino acid binding
GO:0046875 ephrin receptor binding
Biological Process
GO:0009967 positive regulation of signal transduction
GO:0032319 regulation of Rho GTPase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0048013 ephrin receptor signaling pathway
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
IPR001452 SH3 domain
IPR011511 Variant SH3 domain
PFAM PF00017
PF14633
PF00018
PF14604
PF07653
PRINTS PR00401
PR00452
PIRSF
SMART SM00252
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BQ32
UniProt Splice Variant
Entrez Gene 512841
UniGene Bt.19070
RefSeq NP_001179263
HUGO HGNC:2362
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048660
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca