Bos taurus Protein: FLNA
Summary
InnateDB Protein IDBP-684518.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FLNA
Protein Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000030179
InnateDB Gene IDBG-632632 (FLNA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 117 interaction(s) predicted by orthology.
Predicted by orthology
Total 117 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0003779 actin binding
GO:0004871 signal transducer activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0017048 Rho GTPase binding
GO:0017160 Ral GTPase binding
GO:0031267 small GTPase binding
GO:0034988 Fc-gamma receptor I complex binding
GO:0042803 protein homodimerization activity
GO:0044822 poly(A) RNA binding
GO:0048365 Rac GTPase binding
GO:0051015 actin filament binding
Biological Process
GO:0001837 epithelial to mesenchymal transition
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0030036 actin cytoskeleton organization
GO:0031532 actin cytoskeleton reorganization
GO:0034394 protein localization to cell surface
GO:0042177 negative regulation of protein catabolic process
GO:0042384 cilium assembly
GO:0042993 positive regulation of transcription factor import into nucleus
GO:0043113 receptor clustering
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045022 early endosome to late endosome transport
GO:0045184 establishment of protein localization
GO:0050821 protein stabilization
GO:0051220 cytoplasmic sequestering of protein
GO:0051764 actin crosslink formation
GO:0090307 spindle assembly involved in mitosis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0031523 Myb complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001298 Filamin/ABP280 repeat
IPR001715 Calponin homology domain
IPR014756 Immunoglobulin E-set
IPR017868 Filamin/ABP280 repeat-like
PFAM PF00307
PF00630
PRINTS
PIRSF
SMART SM00557
SM00033
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q95LH5
UniProt Splice Variant
Entrez Gene 281165
UniGene Bt.45158
RefSeq NP_001193443
HUGO HGNC:3754
OMIM
CCDS
HPRD
IMGT
EMBL AF260122 DAAA02070092 DAAA02070093 DAAA02070094
GenPept AAK48493