InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CYB5R4

Summary

InnateDB Protein

IDBP-684572.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYB5R4

Protein Name

cytochrome b5 reductase 4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000051953

InnateDB Gene

IDBG-632881 (CYB5R4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005515	protein binding
GO:0016174	NAD(P)H oxidase activity
GO:0016491	oxidoreductase activity
GO:0016653	oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor
GO:0020037	heme binding
GO:0046872	metal ion binding

Biological Process

GO:0006091	generation of precursor metabolites and energy
GO:0006801	superoxide metabolic process
GO:0030073	insulin secretion
GO:0042593	glucose homeostasis
GO:0046677	response to antibiotic
GO:0048468	cell development
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001199 Cytochrome b5-like heme/steroid binding domain
IPR001433 Oxidoreductase FAD/NAD(P)-binding
IPR001834 NADH:cytochrome b5 reductase (CBR)
IPR007052 CS domain
IPR008333 Oxidoreductase, FAD-binding domain
IPR008978 HSP20-like chaperone
IPR017938 Riboflavin synthase-like beta-barrel

PFAM

PF00173
PF00175
PF04969
PF00970

PRINTS

PR00363
PR00406

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite