InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HIC1

Summary

InnateDB Protein

IDBP-684629.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HIC1

Protein Name

hypermethylated in cancer 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000049772

InnateDB Gene

IDBG-632967 (HIC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0042826	histone deacetylase binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0030178	negative regulation of Wnt signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR007087 Zinc finger, C2H2
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR015880 Zinc finger, C2H2-like

PFAM

PF00096
PF00651

PRINTS

PIRSF

SMART

SM00225
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1ML16

UniProt Splice Variant

Entrez Gene

786191

UniGene

RefSeq

XP_003587448

HUGO

HGNC:4909

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02048667 DAAA02048668

GenPept