Version 5.4
Bos taurus Protein: SRR
Summary
InnateDB Protein IDBP-684654.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRR
Protein Name Serine racemase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000005532
InnateDB Gene IDBG-632991 (SRR)
Protein Structure
UniProt Annotation
Function Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0003941 L-serine ammonia-lyase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008721 D-serine ammonia-lyase activity
GO:0016594 glycine binding
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0018114 threonine racemase activity
GO:0030165 PDZ domain binding
GO:0030170 pyridoxal phosphate binding
GO:0030378 serine racemase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006520 cellular amino acid metabolic process
GO:0006563 L-serine metabolic process
GO:0008152 metabolic process
GO:0009069 serine family amino acid metabolic process
GO:0032496 response to lipopolysaccharide
GO:0042866 pyruvate biosynthetic process
GO:0051289 protein homotetramerization
GO:0070178 D-serine metabolic process
GO:0070179 D-serine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme
PFAM PF00291
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A0JNI4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 525340
UniGene Bt.102336
RefSeq NP_001071433
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126700
GenPept AAI26701

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca