Version 5.4
Bos taurus Protein: PLEKHH2
Summary
InnateDB Protein IDBP-684714.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHH2
Protein Name pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000043452
InnateDB Gene IDBG-633022 (PLEKHH2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0030835 negative regulation of actin filament depolymerization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0030027 lamellipodium
GO:0030864 cortical actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR000299 FERM domain
IPR000857 MyTH4 domain
IPR001849 Pleckstrin homology domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR029071 Ubiquitin-related domain
PFAM PF00784
PF00169
PF00373
PRINTS
PIRSF
SMART SM00139
SM00233
SM00295
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MH50
UniProt Splice Variant
Entrez Gene 100299044
UniGene
RefSeq XP_003585496
HUGO HGNC:30506
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02030676
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca