Version 5.4
Bos taurus Protein: DOCK4
Summary
InnateDB Protein IDBP-684726.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOCK4
Protein Name dedicator of cytokinesis 4
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000033637
InnateDB Gene IDBG-632981 (DOCK4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0030165 PDZ domain binding
GO:0030675 Rac GTPase activator activity
GO:0030971 receptor tyrosine kinase binding
GO:0048365 Rac GTPase binding
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0032855 positive regulation of Rac GTPase activity
GO:0060326 cell chemotaxis
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0016020 membrane
GO:0032420 stereocilium
GO:0032421 stereocilium bundle
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR001452 SH3 domain
IPR008936 Rho GTPase activation protein
IPR010703 Dedicator of cytokinesis C-terminal
PFAM PF00168
PF00018
PF14604
PF06920
PRINTS PR00360
PR00452
PIRSF
SMART SM00239
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BMG8
UniProt Splice Variant
Entrez Gene 534227
UniGene Bt.111234
RefSeq XP_002686855
HUGO HGNC:19192
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010689 DAAA02010690 DAAA02010691 DAAA02010692 DAAA02010693 DAAA02010694 DAAA02010695 DAAA02010696 DAAA02010697 DAAA02010698 DAAA02010699
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca