Version 5.4
Bos taurus Protein: IMMP2L
Summary
InnateDB Protein IDBP-684731.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMMP2L
Protein Name Mitochondrial inner membrane protease subunit 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000005770
InnateDB Gene IDBG-633061 (IMMP2L)
Protein Structure
UniProt Annotation
Function Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0001541 ovarian follicle development
GO:0006508 proteolysis
GO:0006627 protein processing involved in protein targeting to mitochondrion
GO:0007283 spermatogenesis
GO:0030728 ovulation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042720 mitochondrial inner membrane peptidase complex
Protein Structure and Domains
PDB ID
InterPro IPR000223 Peptidase S26A, signal peptidase I
IPR015927 Peptidase S24/S26A/S26B/S26C
IPR019759 Peptidase S24/S26A/S26B
PFAM PF00717
PRINTS PR00727
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KI92
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 768034
UniGene Bt.5921
RefSeq NP_001070561
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112723
GenPept AAI12724

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca