Version 5.4
Bos taurus Protein: PIP5K1A
Summary
InnateDB Protein IDBP-684868.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIP5K1A
Protein Name phosphatidylinositol-4-phosphate 5-kinase type-1 alpha
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008015
InnateDB Gene IDBG-633178 (PIP5K1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016307 phosphatidylinositol phosphate kinase activity
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0019900 kinase binding
Biological Process
GO:0008654 phospholipid biosynthetic process
GO:0010761 fibroblast migration
GO:0031532 actin cytoskeleton reorganization
GO:0032863 activation of Rac GTPase activity
GO:0046488 phosphatidylinositol metabolic process
GO:0046854 phosphatidylinositol phosphorylation
GO:0048041 focal adhesion assembly
GO:0060326 cell chemotaxis
GO:0072661 protein targeting to plasma membrane
GO:0097178 ruffle assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex
GO:0005886 plasma membrane
GO:0016607 nuclear speck
GO:0030027 lamellipodium
GO:0032587 ruffle membrane
Protein Structure and Domains
PDB ID
InterPro IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
PFAM PF01504
PRINTS
PIRSF
SMART SM00330
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6QLC5
UniProt Splice Variant
Entrez Gene 100125224
UniGene Bt.64664
RefSeq NP_001096579
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC147915 DAAA02007252
GenPept AAI47916

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca