InnateDB Protein
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IDBP-684943.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CDC42SE1
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Protein Name
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CDC42 small effector protein 1
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000020417
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InnateDB Gene
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IDBG-633248 (CDC42SE1)
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Protein Structure
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Function |
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000095
CRIB domain
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PFAM |
PF00786
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PRINTS |
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PIRSF |
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SMART |
SM00285
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TIGRFAMs |
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Modification |
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SwissProt |
Q5BIS3
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
614042
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UniGene |
Bt.49283
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RefSeq |
NP_001030284
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC102825
BT021151
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GenPept |
AAI02826
AAX31333
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