Version 5.4
Bos taurus Protein: ARNT
Summary
InnateDB Protein IDBP-685022.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARNT
Protein Name aryl hydrocarbon receptor nuclear translocator
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000028023
InnateDB Gene IDBG-633325 (ARNT)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000989 transcription factor binding transcription factor activity
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0004871 signal transducer activity
GO:0004874 aryl hydrocarbon receptor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0017162 aryl hydrocarbon receptor binding
GO:0035326 enhancer binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0001666 response to hypoxia
GO:0001892 embryonic placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0010575 positive regulation vascular endothelial growth factor production
GO:0030154 cell differentiation
GO:0030522 intracellular receptor signaling pathway
GO:0033235 positive regulation of protein sumoylation
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046886 positive regulation of hormone biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000014 PAS domain
IPR001067 Nuclear translocator
IPR001610 PAC motif
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR013655 PAS fold-3
IPR013767 PAS fold
PFAM PF13188
PF13426
PF00010
PF08447
PF00989
PRINTS PR00785
PIRSF
SMART SM00091
SM00086
SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q95KW4
UniProt Splice Variant
Entrez Gene 281010
UniGene Bt.87256
RefSeq NP_776418
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AJ279025 DAAA02007256
GenPept CAC69870

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca