InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CSTF2

Summary

InnateDB Protein

IDBP-685023.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CSTF2

Protein Name

Cleavage stimulation factor subunit 2

Synonyms

CSFT64; cstF-64;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000042892

InnateDB Gene

IDBG-633265 (CSTF2)

Protein Structure

UniProt Annotation

Function

One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Note=Localized with DDX1 in cleavage bodies. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

Biological Process

GO:0006397

mRNA processing

Cellular Component

GO:0005634	nucleus
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
GO:0071920	cleavage body

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8HXM1

PhosphoSite

PhosphoSite-

TrEMBL

F1MVI1

UniProt Splice Variant

Entrez Gene

282588

UniGene

Bt.78724

RefSeq

NP_777110

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AY130297 DAAA02070747 DAAA02070748

GenPept

AAN05427