Version 5.4
Bos taurus Protein: ADM
Summary
InnateDB Protein IDBP-685063.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADM
Protein Name ADMAdrenomedullinAdrenomedullin-11-26Proadrenomedullin N-20 terminal peptide
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000028036
InnateDB Gene IDBG-633364 (ADM)
Protein Structure
UniProt Annotation
Function Hypotensive peptide. May function as a hormone in circulation control (By similarity). {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005515 protein binding
Biological Process
GO:0001570 vasculogenesis
GO:0001843 neural tube closure
GO:0002031 G-protein coupled receptor internalization
GO:0006171 cAMP biosynthetic process
GO:0007507 heart development
GO:0008284 positive regulation of cell proliferation
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0031623 receptor internalization
GO:0043116 negative regulation of vascular permeability
GO:0045766 positive regulation of angiogenesis
GO:0045906 negative regulation of vasoconstriction
GO:0048589 developmental growth
GO:0060670 branching involved in labyrinthine layer morphogenesis
GO:0060712 spongiotrophoblast layer development
GO:0097084 vascular smooth muscle cell development
GO:2001214 positive regulation of vasculogenesis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001710 Adrenomedullin
IPR021116 Procalcitonin/adrenomedullin
PFAM PF00214
PRINTS PR00801
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O62827
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 280713
UniGene Bt.2047
RefSeq NP_776313
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB055107 AJ001613 BC123826
GenPept AAI23827 BAB62176 CAA04866

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca