Version 5.4
Bos taurus Protein: STX7
Summary
InnateDB Protein IDBP-685076.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STX7
Protein Name Syntaxin-7
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022780
InnateDB Gene IDBG-633374 (STX7)
Protein Structure
UniProt Annotation
Function May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). {ECO:0000250}.
Subcellular Localization Early endosome membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0016079 synaptic vesicle exocytosis
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
GO:0031901 early endosome membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000727 Target SNARE coiled-coil domain
IPR006011 Syntaxin, N-terminal domain
IPR010989 t-SNARE
PFAM PF05739
PF00804
PRINTS
PIRSF
SMART SM00397
SM00503
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3ZBT5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 507031
UniGene Bt.37815
RefSeq NP_001071332
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103116
GenPept AAI03117

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca