InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GARS

Summary

InnateDB Protein

IDBP-685143.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GARS

Protein Name

glycyl-tRNA synthetase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025254

InnateDB Gene

IDBG-633427 (GARS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004820	glycine-tRNA ligase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006426	glycyl-tRNA aminoacylation
GO:0015966	diadenosine tetraphosphate biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0030141	secretory granule
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000738 WHEP-TRS
IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR002315 Glycyl-tRNA synthetase
IPR004154 Anticodon-binding
IPR006195 Aminoacyl-tRNA synthetase, class II
IPR009068 S15/NS1, RNA-binding

PFAM

PF00458
PF00587
PF03129

PRINTS

PR01043

PIRSF

SMART

SM00991

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A5D7A2

UniProt Splice Variant

Entrez Gene

408010

UniGene

Bt.20193

RefSeq

NP_001091035

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC140482 DAAA02010899

GenPept

AAI40483