Version 5.4
Bos taurus Protein: SCRN1
Summary
InnateDB Protein IDBP-685193.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCRN1
Protein Name Secernin-1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000021588
InnateDB Gene IDBG-633478 (SCRN1)
Protein Structure
UniProt Annotation
Function Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium. {ECO:0000269PubMed:12221138}.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016805 dipeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006887 exocytosis
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR005322 Peptidase C69, dipeptidase A
PFAM PF03577
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P83939
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 534933
UniGene Bt.65481
RefSeq NP_001104273
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca